Medicus, Vol. 31 No. 2 Osteoporoza, 2022.
Review article
Challenges in Diagnosing Osteoporosis: What Limitations Do We Face?
Ivana Kraljević
Tanja Škorić Polovina
Abstract
Osteoporotic hip and vertebral fractures are associated with a 10 to 20% higher mortality rate in both women and men. Many studies have shown that low BMD is associated with increased fracture risk. However, as many fractures occur in individuals with a T-score better than -2.5, treatment based on BMD alone would miss many patients at high fracture risk who would benefit from treatment. Therefore, evaluating clinical fracture risk factors is essential in the treatment decision. We often use the FRAX risk calculator in clinical work to assess fracture risk. However, the limitations of FRAX should always be considered. Likewise, clinicians should be aware of potential errors in recording and interpreting densitometry to avoid mistakes in diagnosing and monitoring patients with osteoporosis. When analyzing and deciding on therapy, it is also necessary to consider the patient's age and gender and medications that affect bone metabolism.
Keywords
densitometry; FRAX; vertebral fractures; , glucocorticoids; male osteoporosis; premenopausal osteoporosis
Hrčak ID:
291557
URI
Publication date:
17.1.2023.
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