Review article

https://doi.org/10.26800/LV-144-9-10-6

Vaccination against COVID-19 and pregnancy

Nenad Veček orcid.org/0000-0002-0304-7766 ; Zavod za perinatalnu medicinu, Klinika za ženske bolesti i porode, Medicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb
Tatjana Nemeth Blažić ; Hrvatski zavod za javno zdravstvo, Služba za epidemiologiju zaraznih bolesti, Zagreb
Diana Nonković orcid.org/0000-0003-0879-3554 ; Nastavni zavod za javno zdravstvo Splitsko-dalmatinske županije, Služba za epidemiologiju, Split
Branka Arch-Veček ; Klinika za anesteziologiju, reanimatologiju i intenzivno liječenje, Medicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb
Slobodan Mihaljević ; Klinika za anesteziologiju, reanimatologiju i intenzivno liječenje, Medicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb

Abstract

Vaccine is the most effective preventive health measure that reduces the risk of developing a severe form of COVID-19 disease. Since it was determined that pregnant women were prone to develop more severe forms of the disease after being pregnant for 28 weeks with the consequent adverse pregnancy outcome (mainly due to the premature delivery), increased preventive care is required in pregnancy during the pandemic of COVID- 19. Vaccinated pregnant women are at a lower risk for severe forms of disease, lethal outcome, preterm labour and
stillbirth compared with their unvaccinated counterparts, thus the vaccination during pregnancy with mRNA vaccine is recommended by the majority of International Societies for Obstetrics and Gynaecology. The mRNA vaccine safety is equal in pregnant women at any stage of pregnancy, both in women becoming pregnant and the general population as well. It is recommended that pregnant women, regardless of the duration of their pregnancy, along with breastfeeding women, women who are planning a pregnancy or treating infertility should be immediately vaccinated against COVID-19. Vaccination postponement due to organogenesis is not recommended. Both pregnant and puerperal women should be advised to get a booster six months after vaccination. Any pregnant woman should decide for herself whether to get vaccinated, after being informed by a medical professional of vaccine risks and benefits based on professional and scientific arguments.

Keywords

COVID-19 – complications, epidemiology, prevention and control; PREGNANCY COMPLICATIONS, INFECTIOUS – epidemiology, prevention and control, virology; SARS-CoV-2 – pathogenicity; COVID-19 VACCINES – adverse effects, immunology; mRNA VACCINES – adverse effects, immunology; VACCINATION – adverse effects; PREGNANCY OUTCOME – epidemiology; PREMATURE BIRTH – epidemiology

Hrčak ID:

284419

URI

https://hrcak.srce.hr/284419

Publication date:

9.10.2022.

Article data in other languages: croatian

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