Short communication, Note
Effect of Erythropoietin in a Patient with Severe Congestive Heart Failure – A Case Report
Tea Carić
Ozren Đerek
Drago Carić
Abstract
Erythropoietin (EPO), traditionally known as a hematopoietic hormone, has recently been shown to have effects beyond
hematopoiesis such as prevention of neuronal and cardiac apoptosis secondary to ischemia and induction of neoangiogenesis4,5,12,13.
Patients with congestive heart failure (CHF) suffer considerable morbidity and mortality despite advances
in therapy. Anemia, CHF, and chronic kidney insuficiency often coexist and interact to cause or worsen each other
in the so-called cardio-renal anemia syndrome3. Treatment with EPO has shown promise in such patients. The paper reviews
a case of a successful recovery of cardiac function in a patient with a severe CHF during the treatment with EPO.
Keywords
cardio-renal anemia; heart failure; erythropoietin; apoptosis
Hrčak ID:
27191
URI
Publication date:
7.7.2008.
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