Original scientific paper
Long Term Results of Age-Related Macular Degeneration Therapy with Prednisolone Acetate – Special Refer to Peripheral Visual Field Changes
Božidar Vojniković
Damir Kovačević
Sanja Njirić
Miran Čoklo
Abstract
In the north Croatian Adriatic area in the period of seven years (from January 2001 to September 2007) 475 patients
(39 to 80 years of age) with dry form of age related macular degeneration (AMD) were diagnosed. Complete ophthalmologic
examination with special reference to visual field testing (Perimetric analysis) was performed. Peripheral visual field
defects were found in 85% of patients. Elderly patients with more advanced forms of macular degeneration had more peripheral
visual field defects. In 400 patients corticosteroid therapy (5 mg Prednisolonacetate, anterior H-inject, Winthorp)
was administered via parabulbar injections every day/five days. Control group consisted of 75 patients treated
with regular polyvitamine therapy (Lutein, Beta Karoten, Vitamin E). Patients treated with corticosteroids had peripheral
visual field improvements from 10 to 25 degrees and central field improvements from 5 to 20 %. In the control group
treated with vitamins, central visual field showed improvements from 0.5 to 1% in 43 patients but without peripheral visual
field improvements after 6 months.
Keywords
macular degeneration; prednisolone acetate; visual field
Hrčak ID:
27229
URI
Publication date:
7.7.2008.
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