Medicina Fluminensis, Vol. 59 No. 2, 2023.
Original scientific paper
https://doi.org/10.21860/medflum2023_300574
The Association of ABO and RhD Blood Groups with COVID-19 Mortality of Patients Hospitalized in the COVID Ward at General Hospital Karlovac
Maja Kramberger
orcid.org/0009-0009-9035-7356
; Opća bolnica Karlovac, Karlovac, Hrvatska
Zrinka Biloglav
; Škola narodnog zdravlja ‘Andrija Štampar’ Medicinskog fakulteta Sveučilišta u Zagrebu, Katedra za medicinsku statistiku, epidemiologiju i medicinsku informatiku, Zagreb, Hrvatska
Jasminka Talapko
; Sveučilište Josipa Jurja Strossmayera Osijek, Fakultet za dentalnu medicinu i zdravstvo, Osijek, Hrvatska
Ivana Škrlec
orcid.org/0000-0003-1842-930X
; Sveučilište Josipa Jurja Strossmayera Osijek, Fakultet za dentalnu medicinu i zdravstvo, Osijek, Hrvatska
Abstract
Aim: This study aimed to examine the association of ABO and RhD blood groups with COVID-19 mortality of patients hospitalized in the COVID ward at General Hospital Karlovac. Participants and methods: The study included data about 778 patients with COVID-19 hospitalized in the COVID ward at General Hospital Karlovac from March 2020 to the end of December 2021. Data about the hospitalized patients’ age, sex, blood groups, RhD status, comorbidities, oxygen, respirator use, vaccination, and disease course and outcome were obtained from the Hospital Management System. Furthermore, the association of ABO and RhD blood groups with the number of days in the hospital and the mortality rate was examined. Results: The prevalent blood group was O, with 283 patients (36.4%), while the A blood group was the second most common (35.8%). The least common blood group was AB (7.6%). At the time of hospitalization, a small number of patients had been vaccinated, only 8.1%. The overall COVID-19-associated mortality of 25.9% was observed. The mortality rate was 39.7% in blood group A, 24.2% in group B, 23.7% in group AB and 23.7% in group O (P = 0.588). The mortality rate from the COVID-19 disease was higher in RhD-positive (26.4%) compared to RhD-negative individuals (23.7%). The largest number of patients on a respirator (16.5%) were A blood group. Conclusion: The study did not find a significant association between the ABO and RhD blood group and the COVID-19 severity and mortality among patients hospitalized in the COVID ward at General Hospital Karlovac.
Keywords
ABO blood-group system; COVID-19; Croatia; mortality; Rh-Hr blood-group system; SARS-CoV-2
Hrčak ID:
300574
URI
Publication date:
1.6.2023.
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