Professional paper

https://doi.org/10.37797/ig.42.1.5

Neurologic paraneoplastic syndrome in renal cell carcinoma – a diagnosis mislead by the death of a mouse

Marjan Marić orcid.org/0000-0002-5002-3492 ; University Hospital Centre Zagreb, Department of Urology, Zagreb, Croatia
Lorna Stemberger Marić orcid.org/0000-0002-5002-3492 ; University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia
Ivan Kurelac ; University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia
Adriana Vince ; University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia
Željko Kaštelan ; University Hospital Centre Zagreb, Department of Urology, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia
Neven Papić ; University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia

Abstract

Neurologic symptoms secondary to a paraneoplastic syndrome (PNS) may be the presenting manifestation of a previously undiagnosed cancer. This case highlights the potential complexity of the PNS associated with renal cell carcinoma, confusion and delay of diagnosis due to positive mouse bioassay, latter presentation as encephalitic syndrome, positive outcome associated with initial treatment with total plasma exchange, as well as absence of recurrence of neurologic symptoms after complete surgical removal of tumor.

Keywords

paraneoplastic syndrome; encephalitis; renal cell carcinoma

Hrčak ID:

300824

URI

https://hrcak.srce.hr/300824

Publication date:

25.4.2023.

Article data in other languages: croatian

Visits: 1.240 *