Original scientific paper
The Place and Role of Serologic Methods in Detecting Helicobacter Pylori Infection
Marinko Marušić
Vladimir Presečki
Miroslava Katičić
Mara Dominis
Smilja Kalenić
Abstract
The aim of the study was to determine the place and role of serologic methods in detecting Helicobacter pylori (H.
pylori) infection, on the basis of estimated enzyme-linked immunosorbent assay (ELISA) and complement fixation test
(CFT) sensitivity and specificity. A total of 549 patients were included in the study. ELISA and CFT as serologic methods
were compared with invasive methods (rapid urease test – CLO test, culture, histology). The sensitivity of serologic methods
was above 90%, and their specificity was around 80%. Study results confirmed the value, reliability and usefulness
of serologic methods in the detection of H. pylori infection.
Keywords
H. pylori; serology tests; sensitivity; specificity
Hrčak ID:
27583
URI
Publication date:
12.5.2006.
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