Meeting abstract
https://doi.org/10.26800/LV-145-supl2-CR33
Drug - drug interaction in a patient with epilepsy and newly diagnosed paroxysmal atrial fibroundulation
Klara Bardač
; School of Medicine, University of Zagreb, Zagreb, Croatia
Lucija Dafne Blažević
Lucija Nevena Barišić
Iveta Merćep
Abstract
Cytochrome P450 isoenzymes have a major role in the metabolism of xenobiotics. They are mostly found in hepatocytes and oxidize majority of drugs, thus shifting them into their inactive form. Some of them can influence cytochromes’ activity while getting oxidized, simultaneously inducing or inhibiting them. This way, drug activity can be altered and their benefit in the management of the disease limited.
Keywords
anticoagulants; carbamazepine; cytochromes; phenobarbital
Hrčak ID:
303548
URI
Publication date:
23.4.2023.
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