Book review

https://doi.org/10.20471/acc.2023.62.01.27

Simultaneous Metastases of Papillary Thyroid Carcinoma and Neuroendocrine Tumor of the Cecum to Cervical Lymph Nodes: A Case Report

Matija Romić ; Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ivan Blažeković ; Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Neven Mateša orcid.org/0009-0002-5533-9020 ; Department of Pathology and Cytology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Maja Franceschi ; Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ines Šiško-Markoš orcid.org/0000-0001-6425-0701 ; Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Zvonko Kusić ; Croatian Academy of Sciences and Arts, Zagreb, Croatia
Ana Fröbe orcid.org/0000-0002-5834-9841 ; Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Tomislav Jukić orcid.org/0000-0001-5631-164X ; Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia

Abstract

We present a case of a patient with simultaneous cervical lymph node metastasis
of papillary thyroid cancer (PTC) and cecum neuroendocrine tumor (NET). A 45-year-old male
patient with the diagnosis of metastatic NET of the cecum underwent fine needle aspiration (FNA)
of a positron emission tomography with 18F-fluorodeoxyglucose (18F-FDG PET) positive nodule in
the left thyroid lobe. Due to FNA finding suspect of PTC, the patient underwent total thyroidectomy
with central neck dissection. Histopathologic finding revealed PTC of the left thyroid lobe and small
solitary lymph node PTC metastasis in the central neck region. Postoperative evaluation with neck
ultrasound (US) revealed two enlarged suspected lymph nodes in cervical regions III and IV on the
left side of the neck and the patient underwent FNA with measurement of thyroglobulin (Tg) in the
aspirates. The FNA finding of the cervical lymph node in the region III revealed PTC metastasis with
high Tg value in the aspirate, while FNA finding of the cervical lymph node in the region IV revealed
NET metastasis with low Tg value in the aspirate. Postoperative serum Tg value was 17.75 μg/L and
the patient underwent 5550 MBq iodine-131 (I-131) therapy. A year after I-131 therapy, follow-up
neck US demonstrated complete cure of PTC cervical lymph node metastasis in the region III and
stable in size NET cervical lymph node metastasis in the region IV. To our knowledge, this is the first
report of simultaneous occurrence of cervical lymph node metastases of PTC and NET of the cecum.

Keywords

Papillary thyroid cancer; Neuroendocrine tumor; Cervical lymph node; Metastasis

Hrčak ID:

307317

URI

https://hrcak.srce.hr/307317

Publication date:

1.4.2023.

Article data in other languages: croatian

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