Meeting abstract
Safety profile od allergen specific imunotherapy of allergic rhinitis
K. Mitrović
V. Tomic Spiric
; Clinical Center of Serbia, Belgrde, Serbia
Abstract
Background: The aim of the presentation is to determine the safety profile of allergen specific immunotherapy,
the frequency of local and/or systemic reactions, including subcutaneous (SCIT) and sublingual (SLIT)
administrations.
Methods: Our research was carried out in the diagnostic polyclinic section of the Allergology and Immunology
Clinic of the Clinical Center of Serbia in Belgrade. We looked at retrospective insights into medical
documentation, and all statistics was processed in the SPSS software.
Results: Allergen specific immunotherapy (ASIT) is an effective treatment in IgE mediated allergic diseases:
a) allergic rhinitis, with or without conjunctivitis,
b) allergic asthma and
c) hypersensitivity to venomas, with a range of patients from very good tolerance of AIT (no local, no
systemic reactions 67.5 % ) to patients with very poor tolerance of AIT (there was not one case with
anaphylactic shock, 0 % ).
Conclusion: Its advantage as immunomodulatory treatment versus conventional pharmacological is that it
alleviates the clinical picture, prevents the development of new symptoms, sensitizations and progression of
rhinitis in asthma or a more severe disease.
The quality of life is remarkably improved and also exhibits long term effects after the discontinuation of
therapy.
Keywords
Hrčak ID:
308093
URI
Publication date:
19.9.2023.
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