Original scientific paper
Multilayer vs. Monolayer Amniotic Membrane Transplantation for Deep Corneal Ulcer Treatment
I. Dekaris
N. Gabrić
I. Mravičić
Ž. Karaman
J. Katušić
R. Lazić
N. Špoljarić
Abstract
The purpose of the study was to evaluate the efficacy of multilayer amniotic transplantation
(AMT) for reconstruction of corneal stroma and epithelium. Corneal ulcer
(28) was a consequence of a previous infectious or neurotrophic keratitis. In the first
group (17) ulcer was covered with monolayer AM, while in the other group (11) there
were two or more layers of AM situated in the ulcer and the whole cornea was covered
with AM sheet. Monolayer AMT was successful in 64% while the multilayer AMT success
rate was 72%. AM gradually dissolved within 3–6 postoperative weeks. AM transplantation
facilitates rapid healing of corneal epithelium, reduces inflammation and
stimulates epithelial cell regrowth. In eyes with deep corneal ulcer multilayer technique
proved to be better then monolayer procedure.
Keywords
Hrčak ID:
28477
URI
Publication date:
23.7.2001.
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