Review article

https://doi.org/10.21860/medflum2024_313689

Approach to the Psoriasis Treatment - Part Three: Non-Biologic Systemic Therapy

Zala Peterka ; Sveučilište u Rijeci, Medicinski fakultet, Rijeka, Hrvatska
Nika Hlača ; Sveučilište u Rijeci, Medicinski fakultet, Katedra za dermatovenerologiju, Rijeka, Hrvatska; Klinički bolnički centar Rijeka, Klinika za dermatovenerologiju, Rijeka, Hrvatska
Marijana Vičić ; Sveučilište u Rijeci, Medicinski fakultet, Katedra za dermatovenerologiju, Rijeka, Hrvatska; Klinički bolnički centar Rijeka, Klinika za dermatovenerologiju, Rijeka, Hrvatska

Abstract

Psoriasis is a chronic immune-mediated disease that affects 2-5% of the world's population. Most patients with moderate to severe psoriasis require systemic treatment. Despite the development of biological therapy, traditional systemic drugs remain an important therapeutic option due to their efficacy and affordability. The most commonly used traditional drugs are methotrexate, ciclosporin, acitretin, and fumarate. One of the disadvantages of traditional systemic medication is the possibility of side effects, which can be successfully controlled with regular patient monitoring.

Keywords

Acitretin; Cyclosporine; Fumarates; Methotrexate; Psoriasis; Therapeutics

Hrčak ID:

313689

URI

https://hrcak.srce.hr/313689

Publication date:

1.3.2024.

Article data in other languages: croatian

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