Review article
https://doi.org/10.20471/LO.2023.51.02-03.17
Faecal transplantation as a potential new approach in treating colorectal cancer
Ira Renko
; University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, Croatia
Andrija Karačić
; University Hospital Sveti Duh, Zagreb, Croatia
Abstract
Colorectal cancer is one of the leading causes of death in modern times and the most common form of cancer, whose number of patients is growing exponentially. Current treatment methods include surgery, chemotherapy, radiotherapy, and immunotherapy. However, although satisfactory, they have a large number of limiting factors. Inevitably, we consider the additive value of the new methods, such as fecal transplantation. Fecal transplantation is based on suppressing cancer metastasis by establishing a balanced and diverse intestinal microbiome in the affected person. In addition, it induces cancer cell apoptosis with its metabolites. It also stimulates the production of other molecules with the same function, making it a promising approach to treating colorectal cancer.
Keywords
intestinal microbiome; intestinal dysbiosis; fecal transplantation; colorectal cancer
Hrčak ID:
314283
URI
Publication date:
12.2.2024.
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