Original scientific paper

https://doi.org/10.20471/acc.2023.62.03.3

Association between Allergic Reactions and Lip Inflammatory Lesions (Cheilitis)

Tadeja Blagec ; Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Iva Crnarić ; Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Damir Homolak ; Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Nives Pondeljak ; Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Marija Buljan ; Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Liborija Lugović-Mihić orcid.org/0000-0001-7494-5742 ; Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, Croatia *

* Corresponding author.

Abstract

The purpose of this study was to examine the possible association between cheilitis
and allergic reactions, and to use allergy skin tests to identify the allergens that induce allergic
reactions in cheilitis patients (type I and type IV). We included 50 patients with recurrent cheilitis
(reversible cheilitis) who were dermatologically examined and agreed to undergo allergy skin tests,
i.e., patch test and prick test. Additionally, clinical pictures and patient mental stress levels were
examined using the Perceived Stress Scale (PSS). Positive prick tests (atopy) were recorded in 84%
of patients with cheilitis. The most frequently found allergens were contact allergens (54%) (cobalt
chloride, nickel sulfate and thimerosal) and inhalant allergens (46%). The patch test positive subjects
who used cosmetic, hygiene, and decorative products were significantly more likely to have
swollen and red lips than the patch test negative subjects. Also, low stress levels were recorded less
frequently in patients with confirmed allergies than in non-allergic patients. The results indicated a
higher incidence of cheilitis in the people prone to allergies (atopics) and confirmed an association
between cheilitis and allergies. To our knowledge, this is the first study in patients with cheilitis,
which simultaneously analyzed allergies, their clinical features and PSS in the same patients.

Keywords

Cheilitis; Lip inflammation; Allergy; Allergens; Mental stress

Hrčak ID:

314858

URI

https://hrcak.srce.hr/314858

Publication date:

1.11.2023.

Article data in other languages: croatian

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