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Review article

https://doi.org/10.26800/LV-146-supl1-32

The enigma of the HPV-genital infection in the paediatric and adolescent age (brief communication)

Mihael Skerlev *
Suzana Ljubojević Hadžavdić
Slobodna Murat-Sušić
Karmela Husar
Ivana Martinac Ciglar
Anamaria Balić

* Corresponding author.


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Abstract

Anogenital infections caused by Human papillomavirus (HPV) are the most frequently diagnosed Sexually Transmitted Infections (STIs) of viral origin. Anogenital warts (condylomata acuminata) are the most common lesions presented in men, however, during the last decade the other HPV-associated exaggerated lesions such as condylomata plana, penile, scrotal, and anal intraepithelial neoplasias (thus not only cervical), as well as the penile, urine bladder and prostate cancer have been studied a little bit more extensively. The clinical variations might range from clinically invisible, asymptomatic lesions to the bizarre forms of giant condyloma of Buschke-Löwenstein type, including Bowenoid papulosis, Mb. Bowen, different kinds of eryhtroplasias in both men and women and a large spectrum of HPV-induced dermatovenereological entities in genital region including the HPV-associated premalignant and malignant lesions of larynx, oropharynx, mouth cavity etc. In spite of the fact that the clinical manifestations of HPV-genital infections are most frequently observed in the third decade of life, more and more cases have been reported (or registered?) in the paediatric and meno/andropausal age. The complexity of the HPV-genital infections in the paediatric age definitely deserve our special attention providing the specific “child-parent-health provider” relationship in such delicate situation, demanding treatment modalities in paediatric age and the possibility that such clinical lesions might be consequence of the child sexual abuse. A critical, reasonable and reassuring attitude of the health provider is definitely mandatory in these particular situations. Accordingly, we definitely need the HPV vaccination programme to get rid of one of the oldest and up to now unsolved problems of humankind. Approaches to this include prophylactic vaccines such as nonavalent (9v) HPV vaccine for both men and women.

Keywords

HPV; CHILDREN; SPECIFICITIES; HPV VACCINE

Hrčak ID:

316045

URI

https://hrcak.srce.hr/316045

Publication date:

11.4.2024.

Article data in other languages: croatian

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