Case report, case study
Could multisystem inflammatory syndrome in adults after COVID-19 have different presentations in kidney transplant recipients - a report of two cases
Armin Atić
; Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia
*
Ivana Jurić
; Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia
Lea Katalinić
; Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia
Vesna Furić Čunko
; Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia
Ana Strizić
; Department of Nephrology, Clinical Hospital Dubrava, Zagreb, Croatia
Jasmina Matijašević-Škerlj
; Clinical Pharmacy, University Hospital Center Zagreb, Zagreb, Croatia
Zoran Sabljić
; Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia
Nikolina Bašić-Jukić
; Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia
* Corresponding author.
Abstract
Multisystem inflammatory syndrome after COVID-19 (MIS-A) is a consequence of an abnormal inflammatory response after COVID-19 resolution. Current criteria for diagnosis consist of the involvement of several organ systems. We present two cases, one in an immunosuppressed kidney transplant recipient and one in a patient on hemodialysis currently not on immunosuppression. The different clinical presentations and disease development may indicate that the current criteria for MIS-A diagnosis may be inadequate for immunosuppressed patients, as chronic immunosuppression may alter disease presentation. Both patients were treated with corticosteroids and intravenous immunoglobulins, and in both cases the treatment resulted in a prompt resolution of symptoms and stabilization of inflammatory parameters.
Keywords
MIS-A; kidney transplantation; intravenous immunoglobulin; COVID-19
Hrčak ID:
318626
URI
Publication date:
25.6.2024.
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