Review article

https://doi.org/10.46419/vs.56.2.6

Current application of proteomics in the veterinary field – a short summary and literature review

Filip Kajin orcid.org/0000-0002-8329-9233 ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Iva Šmit orcid.org/0000-0001-7685-2785 ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Vladimir Stevanović ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Dina Rešetar Maslov orcid.org/0000-0002-0159-8281 ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Ivana Rubić ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Vladimir Mrljak ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Josipa Kuleš orcid.org/0000-0002-4945-4690 ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska *

* Corresponding author.

Abstract

The biomedical research field’s continuous search for innovative technologies has led to improved disease diagnosis, novel drug discovery, and therapeutic interventions, all aimed at enhancing animal and human health alike. In this context, proteomics has emerged as a critical new technology, focusing on detailed examinations of protein composition, abundance, structure, function, and interactions. Proteomics, the study of the entire set of
proteins expressed by an organism, plays a crucial role in disease diagnosis, drug discovery, and therapeutic interventions in both human and animal health. Proteomics in veterinary medicine and animal health is an evolving field that holds significant promise for fundamental and applied discoveries related to the biology and pathology of domestic and companion species. It encompasses a broad spectrum of applications, including disease diagnosis, comparative medicine, pharmacology, nutrition, reproductive biology, livestock production,
and pathology. By analysing protein profiles and interactions, proteomics contributes to enhancing animal health, welfare, and productivity across various fields of veterinary research and practice. Experimental proteomics in domestic animals offers advantages over the use of rodents, such as the ability to conduct multiple
time-series samplings of biological samples for extensive analysis, allowing for the investigation of experimental and natural disease processes. This review highlights the current application of proteomics in veterinary medicine, focusing on its potential to advance diagnostics, research, and treatments in veterinary science. The current limitations of proteomics are also discussed.

Keywords

veterinary proteomics; biomarker; drug discovery; animal models; bioinformatics

Hrčak ID:

319600

URI

https://hrcak.srce.hr/319600

Publication date:

14.8.2024.

Article data in other languages: croatian

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