Professional paper

https://doi.org/10.46419/vs.56.3.12

Spontaneous Zymbal's gland tumor in a 25-week old Wistar male rat: a case report

Ana I. Faustino-Rocha ; Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), Institute for Innovation, Capacity Building and Sustainability of Agri-food Production (Inov4Agro), Vila Real, Portugal, Department of Zootechnics, School of Sciences and Technology, Évora, Portugal, Comprehensive Health Research Center (CHRC), Évora, Portugal
Paula A. Oliveira orcid.org/0000-0002-1912-1457 ; Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), Institute for Innovation, Capacity Building and Sustainability of Agri-food Production (Inov4Agro), Vila Real, Portugal, Department of Veterinary Sciences, Shool School of Agrarian and Veterinary Sciences (ECAV), University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal *
Ana. M, Calado ; Department of Veterinary Sciences, Shool School of Agrarian and Veterinary Sciences (ECAV), University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal, Animal and Veterinary Research Center (CECAV), Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Vila Real, Portugal
Fernarda Seixas ; Department of Veterinary Sciences, Shool School of Agrarian and Veterinary Sciences (ECAV), University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal, Animal and Veterinary Research Center (CECAV), Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Vila Real, Portugal

* Corresponding author.

Abstract

This work describes a spontaneous Zymbal’s gland tumor in a 25-week old Wistar male rat that had been included in the control sedentary group of an assay of hormone and chemically-induced prostate cancer. The animal exhibited a unilateral, round, ulcerated mass, ventral to the left ear. Histopathologically, it was a non-encapsulated mass composed of solid sheets of basaloid epithelial cells with occasional sebocyte differentiation. Multiple cells presented variable sized eosinophilic granules. The histopathological data were compatible with a basaloid carcinoma, and its location is suggestive of Zymbal’s gland (auditory sebaceous gland) origin.

Keywords

auditory sebaceous gland; chemical carcinogenesis; young rat

Hrčak ID:

321314

URI

https://hrcak.srce.hr/321314

Publication date:

3.11.2024.

Article data in other languages: croatian

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