Short communication, Note
https://doi.org/10.2478/10004-1254-59-2008-1894
Efficacy of Mineral Cationic Carrier Against Sulphur Mustard in Skin Decontamination
Ante Vučemilović
; Institute of Researches and Development of Defense System, Zagreb, Croatia
Mirko Hadžija
; Ruđer Bošković Institute, Zagreb, Croatia
Ivan Jukić
; Institute of Researches and Development of Defense System, Zagreb, Croatia
Abstract
The aim of this study was to evaluate decontamination (absorption) efficacy of a preparation called Mineral Cationic Carrier (MCC®) against skin contamination with sulphur mustard in vivo. MCC® is a synthetic preparation with known ion exchange, absorption efficiency, and bioactive potential. CBA mice were applied increasing doses of sulphur mustard on their skin and MCC® was administered immediately after skin contamination. The results have confirmed the decontamination efficacy of MCC® preparation, corresponding to 8.4 times the LD50 of percutaneous sulphur mustard, and call for further investigation.
Keywords
CBA mice; MCC®; decontamination efficacy; yperite; warfare agent
Hrčak ID:
29562
URI
Publication date:
8.12.2008.
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