Psychiatria Danubina, Vol. 21 No. 1, 2009.
Other
WEIGHT LOSS DURING THERAPY WITH OLANZAPINE ORALLY DISINTEGRATING TABLETS: TWO CASE REPORTS
Oliver Kozumplik
; University Department, Vrapče Psychiatric Hospital, Bolnička cesta 32, Zagreb, Croatia
Suzana Uzun
; University Department, Vrapče Psychiatric Hospital, Bolnička cesta 32, Zagreb, Croatia
Miro Jakovljević
; University Department, Clinical Hospital Zagreb, Kišpatićeva 12, Zagreb, Croatia
Abstract
The aim of this article is to report weight loss in patients with schizophrenia after switching from olanzapine standard oral tablet (SOT) to olanzapine orally disintegrating tablets (ODT).
In the first case report, the patient was switched to olanzapine ODT in daily dosage of 20 mg, while in the second case report, the patient was switched to olanzapine ODT in daily dosage of 15 mg, and weight loss was similar (14 kg vs. 15 kg). Switching patients from olanzapine SOT to olanzapine ODT treatment resulted in significant weight loss that was maintained during 12 months in both case
reports. Further controlled clinical investigations are necessary to evaluate change in weight during treatment with olanzapine ODT, and to improve our understanding of this change.
Keywords
olanzapine; schizophrenia; weight loss; treatment
Hrčak ID:
32771
URI
Publication date:
24.2.2009.
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