Original scientific paper

Comparison of epidural anesthesia with lidocaine-distilled water and lidocaine-magnesium sulfate mixture in goat.

Amin Bigham Sadegh orcid.org/0000-0003-4981-7495 ; Department of Surgery and Radiology, Faculty of Veterinary Medicine, Shahreh-kord University, Shahreh-kord, Iran
Zahra Shafiei ; Resident of Veterinary Surgery, Department of Surgery and Radiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Seifollah Dehghani Nazhvani ; Department of Surgery, School of Veterinary Medicine, Shiraz University, Sadegh, Shiraz, Iran

Abstract

Ruminants are generally not considered good subjects for general anaesthesia mainly because of the hazards of regurgitation and inhalation of ruminal contents or saliva into the lungs if the airway is left unprotected. Thus, regional anaesthesia produced by perineural or epidural injections of anaesthetic agents are most frequently employed in these species. The following study was carried out to compare directly the time of onset and duration of analgesia produced by a lidocaine-MgSO4 combination with that produced by lidocaine-distilled water administration in the epidural space of goats. Seven healthy adult (2 ± 0.5 years of age) native goats (49 ± 3 kg) were selected for this study. Caudal epidural anesthesia was produced in all goats by 2% lidocaine (1 mL/7 kg) with 1 mL distilled water and two weeks later repeated by 2% lidocaine (1 mL/7 kg) with 1 mL of 10% MgSO4. Time of onset, duration, standing and cranial spread of analgesia were recorded. Heart rate, respiratory rate and body temperature were recorded at 0 minutes prior to epidural administrations of each treatments as base line values and at 10, 30, 45 and 60 minutes after the epidural administration of each treatments. Statistical analysis included the paired Student’s t-test and ANOVA (SPSS, soft ware of windows). P<0.05 was considered as a significant level. A significant difference (P<0.05) was noted for the onset of analgesia between lidocaine-distilled water (2.38 ± 0.38 min) and lidocaine-MgSO4 (3.71 ± 0.38 min). Lidocaine-MgSO4 produced analgesia of significantly longer duration (171.85 ± 8.07 min) than that of lidocaine-distilled water (61.42 ± 6.39 min). There were no significant differences in standing time between the two groups. There were no significant differences in HR, RR, and body temperature in comparison with the base line values in the lidocaine-distilled water and lidocaine-MgSO4 groups. Using this combination, long duration obstetrical and surgical procedures could commence relatively soon after epidural injection and could be completed without re-administration of the anesthetic agent.

Keywords

magnesium sulfate; N-Methyl-D-Aspartate; lidocaine; goat; epidural anesthesia

Hrčak ID:

32929

URI

https://hrcak.srce.hr/32929

Publication date:

24.2.2009.

Article data in other languages: croatian

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