Veterinary Archives, Vol. 79 No. 1, 2009.
Original scientific paper
Histopathological changes in broiler chickens fed aflatoxin and cyclopiazonic acid
Raja Kumar
; Department of Veterinary Pathology, Rajiv Gandhi College of Veterinary and Animal Sciences, Puducherry, India
Chidambaram Balachandran
; Department of Veterinary Pathology, Veterinary College and Research Institute, Namakkal, Tamilnadu, India
Abstract
Experimental mycotoxicoses was induced into broiler chickens by feeding 1 ppm afl atoxin (AF) and 20 ppm cyclopiazonic acid (CPA) from 0 to 28 days of age to evaluate the gross and histopathological changes. Grossly, AF and AF-CPA fed birds showed enlargement, yellowish discoloration of the liver while the CPA fed birds showed enlargement and congestion. The CPA and AF-CPA fed birds showed thickening of crop and necrosis and thickening of proventricular mucosa. Histopathologically, degenerative and necrotic changes were observed in the liver, kidneys, intestine, pancreas, heart, pectoral muscle, spleen and bursa of Fabricius of all toxin fed birds. Besides, hyperplastic changes were also observed in the crop, proventriculus and gizzard in the CPA fed birds. The lesions were more marked in the AF-CPA group. The study revealed that AF and CPA in combination could act cumulatively and adversely affect the health of broiler chicken.
Keywords
broiler chicken; aflatoxin; cyclopiazonic acid; pathology
Hrčak ID:
32935
URI
Publication date:
24.2.2009.
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