Professional paper
Phytophotodermatitis in Rijeka Region, Croatia
Maja Lenković
Leo Čabrijan
Franjo Gruber
Marina Saftić
Adalbert Stašić
Vesna Peharda
Zrinka Stanić Žgombić
Abstract
Contact with plants can cause phototoxic or rarely photoallergic reactions. Phototoxic dermatitis (photophytodermatitis)
occurs after contact or ingestion of plants containing furocumarins i.e. psoralens and followed by sun exposure.
Skin lesions develop usually after 24–48 hours with erythema, bulla formation, itch or pain, followed by a long lasting
hyperpigmentation. Furocumarins can be linear i.e. psoralens (5-MOP, 8-MOP), or angular like angelicin and pimpinellin.
Their binding to DNA causes cellular damage. This can happen in florists, gardeners, farmers, horticulturists,
food handlers, and botanists. The plants causing phototoxic reaction can vary with the local flora but are commonly a
member of the family apiaceae (formerly umbelliferae), family rutaceae, leguminosae and moraceae. The authors give
special consideration to the phytophotodermatitis that appeared in their region in spring and summer during a three
year period.
Keywords
photodermatitis; psoralens; apiaceae; moraceae
Hrčak ID:
35117
URI
Publication date:
1.10.2008.
Visits: 1.789 *