Medicina Fluminensis, Vol. 45 No. 3, 2009.
Review article
Desorption electrospray ionization aplication in mass spectrometry
Nenad Benčić
; Pliva Research and development, Pliva, Zagreb, Croatia
Mario Cindrić
; Division of molecular medicine, Laboratory for systemic biomedicine, Rudjer Boskovic Institute, Zagreb, Croatia
Abstract
Desorpti on electrospray ionizati on (DESI) is an ionizati on technique for analysis
in mass spectrometry. It is used as ion source at atmospheric pressure for ionizati on of gases,
liquids and solids at ambient conditi ons. Because of its characteristi cs, when coupled to
mass spectrometer, as a high throughoutput instrumental technique, it can be applied for
various analyti cal purposes such as pepti de and protein analysis, microorganism identi fi cati
on, biological ti ssues imaging, detecti on of drugs and explosives in latent fi ngerprints, metabolite
identi fi cati on, food polutants monitoring and natural compounds characterizati on.
Keywords
Desorption electrospray ionization (DESI); ion source; mass spectrometry
Hrčak ID:
43666
URI
Publication date:
1.9.2009.
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