Original scientific paper

The histological investigation on the testes of mice after an application of capsaicin

Hatice Erdost orcid.org/0000-0003-1547-7293 ; Department of Histology and Embryology, Faculty of Veterinary Medicine, Uludağ University, Bursa, Turkey
Cansel G. Özgüden Akkoç ; Department of Histology and Embryology, Faculty of Veterinary Medicine, Uludağ University, Bursa, Turkey
Nesrin Özfifiliz ; Department of Histology and Embryology, Faculty of Veterinary Medicine, Uludağ University, Bursa, Turkey
Tuncay İlhan ; Department of Histology and Embryology, Faculty of Veterinary Medicine, Uludağ University, Bursa, Turkey
Şerife Tütüncü ; Department of Histology and Embryology, Faculty of Veterinary Medicine, Uludağ University, Bursa, Turkey

Abstract

In the present study we examined the effects of capsaicin, a pungent principle of red hot pepper, on mice testes. Capsaicin was injected subcutaneously at a dose of 1 mg/kg body means everyday for a week each time on 21, 35 and 50-day-olds respectively. The body and testes means of all mice comprising the experiment groups were higher than the control groups. The intertubular compartment of the testes in both group mice showed ++ positive reaction with Oil Red O staining. Spermatogenic cell serial formation took place earlier
compared to the control group. Our study results indicate that capsaicin is relatively non toxic at this dose (1 mg/kg body mean) tested in male mice, no mortality was observed during the study, the experiment groups were hyperactive and spermatogenic series develop earlier.

Keywords

capsaicin; testes; mice; light microscopy

Hrčak ID:

45611

URI

https://hrcak.srce.hr/45611

Publication date:

26.10.2009.

Article data in other languages: croatian

Visits: 2.218 *