Original scientific paper

https://doi.org/10.2478/v10007-010-0007-x

Izolacija i sposobnost hvatanja slobodnih radikala cijanidin 3-O-glikozida iz plodova Ribes biebersteinii Berl.

ABBAS DELAZAR ; School of Pharmacy, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
LALEH KHODAIE ; School of Pharmacy, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
JALIL AFSHAR ; School of Pharmacy, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
LUTFUN NAHAR ; Drug Discovery and Design Research Division, Department of Pharmacy, School of Applied Sciences, University of Wolverhampton, MA Building, Wulfruna Street, Wolverhampton WV1 1LY, West Midland, UK
SATYAJIT D. SARKER ; Department of Pharmacy, School of Applied Sciences, University of Wolverhampton, MM Building, Molineux Street, Wolverhampton WV1 1SB, West Midland, UK

Abstract

Pet cijanidin glikozida, 3-O-sambubiozil-5-O-glukozil cijanidin (1), cijanidin 3-O-sambubiozid (2), cijanidin 3-O-glukozid (3), cijanidin 3-O-(2G-ksilozil)-rutinozid (4) i cijanidin 3-O-rutinosid (5) izolirani su iz metanolnog ekstrakta plodova Ribes biebersteinii Berl. (Grossulariaceae) koristeći reverzno-faznu preparativnu tekućinsku kromatografiju visoke učinkovitosti. Cijanidin glikozidi pokazali su sposobnost hvatanja slobodnih radikala u pokusu s 2,2-difenil-1-pikrilhidrazilom (DPPH). Dobivene su sljedeće RC50 vrijednosti: 9,29 × 106, 9,33 × 106, 8,31 × 106, 8,96 × 106, odnosno 9,55 × 106 mol L1. Strukture glikozida određene su kemijskom hidrolizom i spektroskopijom masa. Ukupni sadržaj antocijanina bio je 1,9 g na 100 g suhih plodova preračunato na cijanidin 3-glukozid.

Keywords

Ribes biebersteinii Berl. (Grossulariaceae); 2,2-difenil-1-pikrilhidrazil (DPPH); cijanidin glikozid; hvatač slobodnih radikala

Hrčak ID:

48281

URI

https://hrcak.srce.hr/48281

Publication date:

1.3.2010.

Article data in other languages: english

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