Original scientific paper

HAMILTON ANXIETY SCALE (HAMA) IN INFERTILE WOMEN WITH ENDOMETRIOSIS AND ITS CORRELATION WITH MAGNESIUM LEVELS IN PERITONEAL FLUID

Elijana Garalejić ; University Clinic of Gynecology and Obstetrics “Narodni Front”, Narodni front 62, 11000 Belgrade, Serbia
Dragana Bojović-Jović ; University Clinic of Gynecology and Obstetrics “Narodni Front”, Narodni front 62, 11000 Belgrade, Serbia
Aleksandar Damjanović ; Institute of Psychiatry, University of Belgrade, School of Medicine, Serbia
Biljana Arsić ; University Clinic of Gynecology and Obstetrics “Narodni Front”, Narodni front 62, 11000 Belgrade, Serbia
Igor Pantić ; Institute of Med. Physiology, University of Belgrade, School of Medicine, Višegradska 26/II, 11000, Belgrade, Serbia
Drenka Turjačanin-Pantelić ; Institute of Med. Physiology, University of Belgrade, School of Medicine, Višegradska 26/II, 11000, Belgrade, Serbia
Milan Perović ; Clinical Hospital Centre, Zemun, Serbia

Abstract

Background: Endometriosis is a complex disease that can result in substantial morbidity, including chronic pain, dysmenorrhea and dyspareunia. There are contradictory reports regarding the connection between acute and chronic stress and magnesium levels in body fluids.
Subjects and methods: A prospective study included 87 patients undergoing laparoscopy. The study group included 40 women with endometriosis and the control group consisted of 47 women with other causes of infertility. The levels of fright were determined using HAMA scale. The measurements of Mg levels were performed using biochemical analyzer “Monarch Plus”.
Results: One day before the operation, HAMA score was 9.54 ±7.34 in the women with endometriosis, and 6.69 ± 5.51 in the women without endometriosis. The morning before the operation, HAMA score was 8.64 ± 8.10 in the women with endometriosis, and 4.29±2.29 in the women without endometriosis. The second
postoperative day, HAMA score was 8.96±7.60 in the women with endometriosis and 6.92±5.16 in the women without endometriosis. Higher HAMA score in the women with endometriosis, in comparison with the control group, in all three time periods has been found, but the differences were not statistically significant (p>0.05). A negative correlation between the concentration of Mg in peritoneal fluid
and HAMA score was found in the control group (p<0.01).
Conclusions. In infertile women without endometriosis a correlation between Mg concentration in peritoneal fluid and HAMA score was found. No such correlation was found in the women with endometriosis, possibly due to a systemic disorder in endometriosis that might affect Mg transport through the cell membrane.

Keywords

endometriosis; HAMA scale; Mg

Hrčak ID:

48619

URI

https://hrcak.srce.hr/48619

Publication date:

10.2.2010.

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