Preliminary communication
Aplastic Crisis Induced by Human Parvovirus B19 as an Initial Presentation of Hereditary Spherocytosis
Dubravka Čaržavec
Petar Gašina
Ankica Vasilj
Sandra Kojić Katović
Abstract
The association between aplastic crisis and human parvovirus (HPV) B19 infection has been described in patients with hereditary spherocytosis (HS). Most cases of aplastic crisis in patients with HS induced by HPV B19 have been reported in children and adolescents. In this paper, we describe an aplastic crisis induced by HPV B19 in the 34 year old female as an initial presentation of HS. Although other viral illnesses cause some decompensation in HS, the anemia is rarely as profound as seen in acute HPV B19 infections15.
Keywords
hereditary spherocytosis; human parvovirus; aplastic crisis; giant pronormoblasts
Hrčak ID:
56493
URI
Publication date:
30.6.2010.
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