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Review article

Sex Hormones and Gender Effects following Trauma-Hemorrhage

Irshad H. Chaudry ; Center for Surgical Research, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA, Boshell Diabetes Building, 1808 7th Avenue South Birmingham, AL 35233, USA
Fariba Moeinpour ; Center for Surgical Research, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA, Boshell Diabetes Building, 1808 7th Avenue South Birmingham, AL 35233, USA
Wen-Ke Wang ; Center for Surgical Research, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA, Boshell Diabetes Building, 1808 7th Avenue South Birmingham, AL 35233, USA
Shaolong Yang ; Center for Surgical Research, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA, Boshell Diabetes Building, 1808 7th Avenue South Birmingham, AL 35233, USA
Raghavan Raju ; Center for Surgical Research, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA, Boshell Diabetes Building, 1808 7th Avenue South Birmingham, AL 35233, USA
William B. Hubbard ; Center for Surgical Research, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA, Boshell Diabetes Building, 1808 7th Avenue South Birmingham, AL 35233, USA


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Abstract

Trauma is the leading cause of death in the industrialized world between the ages of one and 40. A number of risk factors
including age and gender have been implicated in this regard. It is therefore not surprising that the majority of trauma victims
are young males. Their mortality rate following trauma is not only higher compared to females, but they are also more
prone to subsequent sepsis. Age and gender are therefore important factors in the prevalence of traumatic injury as well
as in susceptibility to subsequent septic complications.

Keywords

trauma; mortality; age; gender; sex hormones; sepsis; cardiovascular/ immunological alterations

Hrčak ID:

59432

URI

https://hrcak.srce.hr/59432

Publication date:

1.9.2010.

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