Paediatria Croatica, Vol. 54 No. 4, 2010.
Professional paper
TUMOUR NECROSIS FACTOR INHIBITORS IN TREATMENT OF A CHILD WITH JUVENILE IDIOPATHIC ARTHRITIS AND ASSOCIATED UVEITIS
Ivana Kolić
; Klinika za dječje bolesti, Klinički bolnički centar Rijeka
Vojko Rožmanić
Maja Novak Stroligo
Zvjezdana Alpeza Dunato
Srđan Banac
Neven Čače
Abstract
The most common rheumatic disease associated with uveitis in childhood is juvenile idiopathic arthritis (JIA) and it occurs in about 15% of patients. Females, younger than 10 years of age, with oligoarticular, antinuclear antibody positive JIA, are at the highest risk for developing chronic uveitis. The course of uveitis is unpredictable with frequent complications, of which cataract and glaucoma as the most common. Therapeutic approach is individual and still remains a challenge for paediatric rheumatologists and ophthalmologists. Biological drugs were introduced fifteen years ago as an alternative mode of therapy with encouraging results. We present a patient with a polyarticular type of JIA and associated uveitis, treated with tumour necrosis factor inhibitors.
Keywords
ARTHRITIS, JUVENILE RHEUMATOID; RECEPTORS, TUMOR NECROSIS FACTOR; UVEITIS
Hrčak ID:
64943
URI
Publication date:
22.12.2010.
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