Review article

Traditional systemic therapy – role in the treatment of psoriasis

Marijana Kurilić ; Department of dermatovenerology, Faculty of medicine, University of Rijeka, Croatia
Ines Brajac ; Department of dermatovenerology, Faculty of medicine, University of Rijeka, Croatia
Larisa Prpić-Massari ; Department of dermatovenerology, Faculty of medicine, University of Rijeka, Croatia
Marija Kaštelan ; Department of dermatovenerology, Faculty of medicine, University of Rijeka, Croatia

Abstract

Psoriasis is one of the most common chronic inflammatory skin disease worldwide.
While mild forms of the disease can be successfully controlled by applying local
therapy, one third of patients with moderately severe to severe form of psoriasis, requires
the application of systemic therapy. As indicated in many clinical studies, the conventional
drugs for systemic use in so far experience have shown high efficacy in treating
psoriasis. Methotrexate, cyclosporin and acitretin are cost affordable and provide excellent
disease control. Their application is limited only by the possibility of serious side effects,
which can be successfully controlled and kept to a minumum through carefully
monitoring of patient.

Keywords

acitretin; cyclosporin; methotrexate; psoriasis; systemic therapy

Hrčak ID:

66089

URI

https://hrcak.srce.hr/66089

Publication date:

7.3.2011.

Article data in other languages: croatian

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