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Medicina Fluminensis : Medicina Fluminensis, Vol. 47 No. 1, 2011.

Original scientific paper

Penetrating keratoplasty in patients with keratoconus

Iva Dekaris orcid id orcid.org/0000-0003-4133-9783 ; Special hospital for opthalmology Svjetlost, Zagreb, Croatia
Nikica Gabrić ; Special hospital for opthalmology Svjetlost, Zagreb, Croatia
Maja Pauk ; Special hospital for opthalmology Svjetlost, Zagreb, Croatia
Nataša Drača ; Special hospital for opthalmology Svjetlost, Zagreb, Croatia
Ivana Mravičić ; Special hospital for opthalmology Svjetlost, Zagreb, Croatia
Ante Barišić ; Special hospital for opthalmology Svjetlost, Zagreb, Croatia

Full text: croatian pdf 1.378 Kb

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Abstract

Aim: Keratoconus is the most common indication for corneal transplantation with
high success rate and low number of complications. The aim of this study was to investigate
the level and speed of visual recovery after penetrating keratoplasty (PK) for keratoconus
patients in first year after transplantation. Patients and methods: This prospective study includes
38 keratoconus patients which underwent PK in Eye Clinic Svjetlost in one year. All
patients had best corrected visual acuity (BCVA) ≤ 0.3 and were unable to wear contact lens.
In 31 patients PK was performed for the first time, while in 7 patients it had been already
performed on the other eye. Results: Graft remained clear in 100 % of patients in first 6
months and in 97.7 % in 1 year observation period. Average BCVA after 1 month was 0.53 ±
0.23 (P < 0.001), after 6 months 0.69 ± 0.22 (P < 0.001) and after 1 year (n = 25) it was 0.81 ±
0.14 (P < 0.001). The leading postoperative complication was high postoperative astigmatism
(>4dcyl) in 44.7 % of patients, graft reaction in 13.2 %, intraocular pressure elevation in
5.2 %, graft rejection in 2.6 % and cataract formation in 2.6 % of patients. Discussion: Lamellar
keratoplasty is often suggested as method of choice in keratoconus treatment. In this
study we have shown that a conventional PK gives adequately good success rate. Conclusion:
Penetrating keratoplasty is effective method in treating keratoconus patients with low
visual acuity unable to wear contact lens. Success rate is 97.7 %. The most frequent complication
is high postoperative astigmatism which occurs in 44.7 % of patients.

Keywords

corneal transplantation; endothelial cell density; keratoconus

Hrčak ID:

66091

URI

https://hrcak.srce.hr/66091

Publication date:

7.3.2011.

Article data in other languages: croatian

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