Croatica Chemica Acta, Vol. 77 No. 1-2, 2004.
Izvorni znanstveni članak
Synthesis of 8-Aza-3-deazaisoguanosine by a Novel Ring Closure of Dinitriles by Sodium Alkoxides
Marjan Ješelnik
; National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia
Suzana Jakša
; National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia
Jože Kobe
; National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia
Sažetak
This communication describes a convenient, direct ring closure of a novel 4-cyano-5-cyanomethyl-1-(β-D-ribofuranosyl)-1,2,3-triazole under basic conditions into 4-amino-6-alkoxy-1-(β-D-ribofuranosyl)-1,2,3-triazolo[4,5-c]pyridine, which can be easily transformed to 8-aza-3-deazaisoguanosine.
Ključne riječi
synthesis; 8-aza-3-deazaisoguanosine; ring closure of dinitriles
Hrčak ID:
102659
URI
Datum izdavanja:
31.5.2004.
Posjeta: 1.188 *