Uvodnik
https://doi.org/10.3325/cmj.2015.56.525
The effect of 25- hydroxyvitamin D levels on QT interval duration and dispersion in type 2 diabetic patients
Demet Ozgil Yetkin
; Department of Endocrinology Kolan International Hospital,Istanbul, Turkey
Belgin Kucukkaya
; Department of Internal Medicine, Bayindir Hospital, Istanbul, Turkey
Mehtap Turhan
; Department of Biochemistry Bayindir Hospital, Istanbul, Turkey
Merve Oren
; Department of Public Health Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey
Sažetak
Aim To assess the relationship between corrected QT (QTc)
interval and vitamin 25-hydroxyvitamin D levels (25-OHD)
deficiency in type 2 diabetic patients.
Methods The study included 253 patients with type 2 diabetes
and 170 age-matched controls treated between
October and December 2013. QTc duration and QTc dispersion
were measured on ECG recordings and 25-OHD,
calcium, phosphorus, and blood glucose levels were determined.
Results Patients with diabetes had significantly longer QTc
duration and QTc dispersion than controls (P < 0.001 and
P < 0.001 respectively). Diabetic patients with prolonged
QTc duration were older and had longer diabetes duration
and higher HbA1c levels than patients with normal QTc interval.
They significantly more frequently had 25-OHD deficiency
(P < 0.001), but had similar calcium and phosphorus
levels. Diabetic patients with prolonged QTc dispersion
were of similar age and had similar diabetes duration
and HbA1c levels as patients with normal QTc dispersion.
They significantly more frequently had 25-OHD deficiency
(P = 0.010), but had similar calcium and phosphorus levels.
Conclusion This study showed prolonged QTc duration
and QTc dispersion in patients with type 2 diabetes, especially
those with 25-OHD deficiency.
Ključne riječi
Hrčak ID:
153075
URI
Datum izdavanja:
15.12.2015.
Posjeta: 1.249 *