Izvorni znanstveni članak

https://doi.org/10.20471/acc.2016.55.02.13

Ovarian teratoma in routine biopsy material during a five-year period

Marina Kos orcid.org/0000-0002-9179-6096 ; Ljudevit Jurak Clinical Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia
Jasmina Nikić ; Ljudevit Jurak Clinical Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Tanja Leniček ; Ljudevit Jurak Clinical Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Sažetak

Teratomas are tumors derived from germ cells, most frequently arising in the gonads. The aim of this study was to determine the number of ovarian teratomas diagnosed in the routine biopsy material at Ljudevit Jurak Clinical Department of Pathology, Sestre milosrdnice University Hospital Center during a 5-year period, as well as their clinical, gross and microscopic characteristics. Teratomas accounted for 48.6% (n=166) of primary ovarian tumors. The patient mean age
was 34.74±12.37 years. Difference in the incidence of teratoma between the left and right ovary was not significant; bilateral teratoma was found in 13 patients. Teratomas were detected by ultrasonography in 115 (69.27%) cases and the rest were found during surgery performed for other indications. Most teratomas (n=161; 96.9%) were mature and cystic (dermoid cysts). Mature and solid teratomas were diagnosed in 5 (3.01%), ovarian struma in 2 (1.8%) cases and strumal carcinoid in 1 (1.2%) case. Mature cystic teratomas contained sebaceous material in 123 (76.8%) cases, and a total of 16 teeth were found; 157 (94.5%) teratomas measured <10 cm in largest diameter. Microscopically, mature cystic teratomas most frequently contained ectodermal (skin with appendages, mature glia and nerve ganglia) and mesodermal (fibrous, fat tissue, cartilage and bone) tissues. Frequently found tissues of endodermal origin were respiratory and intestinal epithelia. Small foci of thyroid tissue were found in 20 (12%) teratomas. Chronic granulomatous foreign body reaction in the wall of mature cystic teratomas was found in 11 (6.8%) tumors.

Ključne riječi

Teratoma – diagnosis; Struma ovarii – diagnosis; Carcinoid tumor

Hrčak ID:

164863

URI

https://hrcak.srce.hr/164863

Datum izdavanja:

1.6.2016.

Podaci na drugim jezicima: hrvatski

Posjeta: 7.614 *