Acta clinica Croatica, Vol. 58. No. 3., 2019.
Ostalo
https://doi.org/10.20471/acc.2019.58.03.19
Aggressive Progression of Takayasu’s Arteritis in Infancy: A Case Report
Roman Pavić
orcid.org/0000-0002-9780-2506
; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Traumatology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Robert Blažeković
; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Surgery, Dubrava University Hospital, Zagreb, Croatia
Dalibor Divković
; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Pediatric Surgery, Osijek University Hospital Centre, Osijek, Croatia
Ksenija Marjanović
; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Pathology and Forensic Medicine, Osijek University Hospital Centre, Osijek, Croatia
Mirna Sipl
; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Pediatrics, Osijek University Hospital Centre, Osijek, Croatia
Sažetak
Takayasu’s arteritis (TA) affects the aorta and its branches. Immunosuppressants are the usual course of therapy, while surgery has been used in acute cases. There is only scant information on TA in infancy, and the nonspecific symptoms in the initial stage of the disease make the diagnosis difficult and delayed, thus increasing the mortality rate. We describe a case of aggressive progression of TA in an infant. This child was the youngest to be affected with the disease as reported in the literature. A 3.5-month-old boy pre-sented with cyanosis of both legs, tachycardia and antithrombin III deficiency. Computed tomography angiography (CTA) revealed thrombosis of distal aorta and both iliac arteries. Thrombectomy was per-formed at the level of both common femoral arteries. In addition, thigh amputation of the left leg had to be performed. TA was diagnosed postmortem with thrombosis of the distal aorta, its branches and upper mesenteric artery which was not occluded on previous CTA, glomerulonephritis and pulmonary paren-chymal granulomatous infiltrations.
Ključne riječi
Takayasu arteritis; Infant; Thrombosis; Immunosuppressive agents; Case reports
Hrčak ID:
230275
URI
Datum izdavanja:
1.9.2019.
Posjeta: 2.028 *