Izvorni znanstveni članak

Study on the Lewis Acid-promoted Aza-Diels – Alder Reaction of Azetidin-2-one-tethered Imines with Siloxydienes in the Asymmetric Synthesis of 2-Aryl(alkyl)-2,3-dihydro-4-pyridones

Tanja Poljak ; Ruđer Bošković Institute, Zagreb, Croatia; GlaxoSmithKline Research Centre Zagreb Ltd., Zagreb, Croatia
Krešimir Molčanov ; Ruđer Bošković Institute, Zagreb, Croatia
Davor Margetić ; Ruđer Bošković Institute, Zagreb, Croatia
Ivan Habuš ; Ruđer Bošković Institute, Zagreb, Croatia

Sažetak

trans-3-Amino-b-lactams were evaluated as the chiral building blocks in the aza-Diels – Alder
reaction of azetidin-2-one-tethered imines with siloxydienes under Lewis acid catalysis, as a
route for the asymmetric synthesis of 2-aryl(alkyl)-2,3-dihydro-4-pyridones.

Ključne riječi

beta-lactam; imine; pyridone; aza-Diels – Alder reaction; Lewis acid

Hrčak ID:

31180

URI

https://hrcak.srce.hr/31180

Datum izdavanja:

31.12.2008.

Posjeta: 2.422 *