Acta clinica Croatica, Vol. 62. No. 4, 2023.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2023.62.04.16
Retrospective Observational Study of Vitamin D Status in Neurological Patients
Lucija Zadro Matovina
orcid.org/0009-0007-2350-4702
; Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; University of Zagreb, School of Dental Medicine, Zagreb, Croatia
*
Helena Trputac
; Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Antonia Nicinger
; Department of Neurology, Virovitica General Hospital, Virovitica, Croatia
Petra Magdalena Kes
; University of Zagreb, School of Dental Medicine, Zagreb, Croatia
Vanja Bašić Kes
; Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; University of Zagreb, School of Dental Medicine, Zagreb, Croatia
* Dopisni autor.
Sažetak
The main objective of this study was to investigate the prevalence of insufficient serum
25-hydroxyvitamin D level in a sample of neurological patients and to compare it to the estimate in
the general Croatian population. The secondary aim was to test for the possible significant differences in
vitamin D2 insufficiency between the groups of patients according to gender, season, region, vitamin D3
supplementation, and diagnosis of autoimmune disease. This retrospective study involved 371 neurological
patients in one-year period. The data collected included gender, age at the time of admission, region,
season at the time of admission, main neurological diagnosis at discharge, serum 25-hydroxyvitamin D
level at the time of hospitalization, and use of vitamin D3 substitutes prior to hospitalization. The proportion
of neurological patients with 25-hydroxyvitamin D insufficiency (<75 nmol/L) was estimated at
74.66% (95% confidence interval, p<0.0001), which is slightly lower than in the Croatian general population.
There were no significant differences in 25-hydroxyvitamin D insufficiency according to gender,
season and region. Significant differences in 25-hydroxyvitamin D insufficiency were found according to
vitamin D3 supplementation and diagnosis of autoimmune disease.
Ključne riječi
Vitamin D deficiency; Multiple sclerosis; Autoimmune diseases
Hrčak ID:
320576
URI
Datum izdavanja:
31.12.2023.
Posjeta: 200 *