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Meeting abstract

https://doi.org/10.15836/ccar2024.619

Fulminant myocarditis: a critical and urgent diagnosis with serious prognostic implications: a case report

Petra Taboršak orcid id orcid.org/0009-0002-2016-5868 ; University Hospital Centre Zagreb, Zagreb, Croatia
Ana Marinić orcid id orcid.org/0000-0002-9349-8172 ; University Hospital Centre Zagreb, Zagreb, Croatia


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Abstract

Keywords

fulminant myocarditis; acute heart failure; extracorporeal membrane oxygenation

Hrčak ID:

328955

URI

https://hrcak.srce.hr/328955

Publication date:

13.12.2024.

Visits: 351 *



Introduction: Fulminant myocarditis is a rapidly progressive inflammatory disease of the myocardium, which consists of cardiac muscle cells responsible for cardiac contractions and is among the leading causes of sudden cardiac death in young people. Patients are in poor general condition, hemodynamically unstable and require urgent care. Fulminant myocarditis can quickly progress to multiorgan failure. (1,2) This paper presents a case of fulminant myocarditis of most likely viral origin, followed by a picture of cardiogenic collapse.

Case report: 19-year-old female patient reported to the Emergency Department due to nausea, vomiting, lack of appetite and fever up to 39°C. The laboratory findings showed moderately elevated inflammatory parameters with significantly elevated cardioselective enzymes and signs of heart failure. Cardiac ultrasound revealed impaired heart function (left ventricular ejection fraction 35%). The condition rapidly deteriorated in the manner of fulminant myocarditis, and despite intensive pharmacological support, there was a cardiac arrest. During cardiopulmonary resuscitation, a veno-arterial extracorporeal membrane oxygenation (ECMO) was established as a bridge to further treatment strategies. The course of treatment was complicated by the development of ‘ECMO lung,’ and an Impella CP device. Along with Impella and inotropic support, the patient’s hemodynamic stability was monitored and V-A ECMO was soon removed using a surgical technique, but only minimal recovery of cardiac function was monitored. Finally, the left ventricular assist device (LVAD) pump is left placed, with which the patient is hemodynamically stable. The course of hospitalization was complicated by multiple infectious events in the form of sepsis and multiple pleural effusions. Throughout the entire hospitalization, a holistic approach was used with the daily psychological and pharmacological support and nutrition counseling, which was one of the leading obstacles which needed to be overcome. After 6 months of hospitalization, the patient is discharged home in good general condition.

Conclusion: Fulminant myocarditis is one of the leading causes of acute heart failure in young people. The complexity of care for patients with fulminant myocarditis cannot be overstated. Nurses must coordinate multidisciplinary teams, administer intricate treatment regimens, and provide emotional support to patients and their families. Their expertise in managing mechanical circulatory support devices, such as ECMO and LVADs, is vital to improving patient outcomes.

LITERATURE

1 

Gupta S, Markham DW, Drazner MH, Mammen PP. Fulminant myocarditis. Nat Clin Pract Cardiovasc Med. 2008 November;5(11):693–706. https://doi.org/10.1038/ncpcardio1331 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/18797433

2 

McCarthy RE 3rd, Boehmer JP, Hruban RH, Hutchins GM, Kasper EK, Hare JM, et al. Long-term outcome of fulminant myocarditis as compared with acute (nonfulminant) myocarditis. N Engl J Med. 2000 March 9;342(10):690–5. https://doi.org/10.1056/NEJM200003093421003 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/10706898


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