Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2023.64.179
The effect of high standard uptake value in lung cancer metastatic lesions on survival
Suphi Aydin
; Department of Thoracic Surgery, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
*
Aydın Balci
; Department of Pulmonology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
Ahmet Dumanlı
; Department of Thoracic Surgery, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
Leyla Nesrin Acar
; Department of Thoracic Surgery, SBÜ Ankara Keçiören Atatürk Sanatoryum Pulmonology and Thoracic Surgery Training and Research Hospital, Ankara, Turkey
Murat Ayşin
; Department of Public Health, Katip Celebi University, Faculty of Medicine, Izmir, Turkey
Adem Gencer
; Department of Thoracic Surgery, Afyonkarahisar Public Hospital, Afyonkarahisar, Turkey
Gürhan Öz
; Department of Thoracic Surgery, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
Hacer Demir
; Department of Internal Medicine and Medical Oncology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
Sena Ece Davarc
; Department of Internal Medicine and Medical Oncology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
* Dopisni autor.
Sažetak
Aim To assess how metastatic lesions with a higher maximum standard uptake value than the primary tumor affect
survival in patients with lung cancer.
Methods The study enrolled 590 stage-IV lung cancer patients treated at Afyonkarahisar Health Sciences University Hospital between January 2013 and January 2020. We
retrospectively collected data on histopathological diagnosis, tumor size, metastasis site, and maximum standard
involvement values of primary metastatic lesions. Lung
cancers with the maximum standard uptake value of the
primary tumor higher than that of the metastatic lesion
were compared with lung cancers with the maximum
standard uptake value of the primary tumor lower than
that of the metastatic lesion.
Results In 87 (14.7%) patients, the maximum standard uptake value was higher in the metastatic lesion than in the
primary lesion. These patients experienced significantly
higher mortality risk in both univariate and multivariate
survival analyses (adjusted hazard ratio 2.25 [1.77-2.86],
<0.001) and had shorter median survival (5.0 [4.2-5.8] vs
11.0 [10.2-11.8] months, P<0.001).
Conclusions The maximum standard uptake value could
be a potential new prognostic factor for survival in lung
cancer.
Ključne riječi
Hrčak ID:
331533
URI
Datum izdavanja:
30.6.2023.
Posjeta: 247 *