Acta Pharmaceutica, Vol. 60 No. 4, 2010.
Izvorni znanstveni članak
https://doi.org/10.2478/v10007-010-0033-8
Antimicrobial activity of some synthesized glucopyranosyl-pyrimidine carbonitrile and fused pyrimidine systems
HAYAM H. SAYED
; Photochemistry Department, National Research Centre, 12622 Dokki, Cairo, Egypt
HEBAT-ALLAH S. ABBAS
; Photochemistry Department, National Research Centre, 12622 Dokki, Cairo, Egypt
EMAN M. H. MORSI
; Photochemistry Department, National Research Centre, 12622 Dokki, Cairo, Egypt
ABD EL-GALIL E. AMR
; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
NAYERA A. M. ABDELWAHAD
; Chemistry of Natural and Microbial Product Department, National Research Centre, 12622 Dokki, Cairo, Egypt
Sažetak
3-Amino-5-(4-chlorophenylamino)-4-cyanofuran-2-carboxamide (2) was used as the key molecule for preparation of various furo- pyrimidines 3-9 and formation of spiro-cycloalkane furopyrimidines 10, 11. Also, poly fused heterocyclic compounds 13-17 were prepared from compound 2. The synthesized compounds were screened for their antimicrobial activity.
Ključne riječi
pyrimidine; glucopyranosyl-pyrimidine; oxazine; antimicrobial activity
Hrčak ID:
59305
URI
Datum izdavanja:
1.12.2010.
Posjeta: 2.710 *