Pregledni rad
Alcohol Dehydrogenase from Lactobacillus brevis: A Versatile Robust Catalyst for Enantioselective Transformations
S. Leuchs
; DECHEMA Karl-Winnacker-Institut, Frankfurt am Main, Germany
L. Greiner
; DECHEMA Karl-Winnacker-Institut, Frankfurt am Main, Germany; Institut für Technische und Makromolekulare Chemie, RWTH Aachen University, Aachen, Germany
Sažetak
The alcohol dehydrogenase from Lactobacillus brevis (LbADH) is a versatile catalyst for enantioselective reduction of ketones. Its substrate scope is wide with high regio- and enantioselectivity. In this critical review, we have gathered the information available on the substrate scope as well as the applications reported. Quantitative information such
as productivity per catalyst, space-time yield (STY), cofactor utilisation, and stability are derived to allow comparison and assessment of practical value.
Ključne riječi
Biocatalysis; alcohol dehydrogenase; Lactobacillus brevis; critical review; application
Hrčak ID:
69863
URI
Datum izdavanja:
30.6.2011.
Posjeta: 4.244 *