Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2014.55.377
Idiopathic cerebrospinal fluid overproduction: case-based review of the pathophysiological mechanism implied in the cerebrospinal fluid production
Gianluca Trevisi
; Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
Paolo Frassanito
; Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
Concezio Di Rocco
; Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy
Sažetak
Cerebrospinal fluid (CSF) overproduction results from either
CSF infection or choroid plexus hypertrophy or tumor,
with only a single idiopathic case described so far.
We report a unique case of a male infant with Crouzon
syndrome who presented with intracranial hypertension,
caused by up to 4-fold increase in CSF daily production.
Conditions related to CSF overproduction, namely central
nervous system infections and choroid plexus hypertrophy
or tumor, were ruled out by repeated magnetic resonance
imaging and CSF samples. Medical therapy failed to reduce
CSF production and the patient underwent several shunting
procedures, cranial expansion, and endoscopic coagulation
of the choroid plexus. This article thoroughly reviews
pertinent literature on CSF production mechanisms and
possible therapeutic implications.
Ključne riječi
Hrčak ID:
129943
URI
Datum izdavanja:
15.8.2014.
Posjeta: 1.503 *