Croatica Chemica Acta, Vol. 65 No. 4, 1992.
Izvorni znanstveni članak
Secondary Structure of Membrane Proteins: Prediction with Conformational Preference Functions of Soluble Proteins
Davor Juretić
; Department of Physics, University of Split, Nikole Tesle 12, 58000 Split, Croatia
Sažetak
Conformational preference functions are derived from the statistical analysis of the data base of soluble protein structures. These functions use local sequence information to modify the Chou-Fasman’s preference of a given residue in a protein for secondary conformation. The secondary structure prediction algorithm that compares preferences is constructed. For the testing set of 14 membrane polypeptides the prediction accuracy is 78% in the three state model and 90% for the a-helix residues alone. Correlation coefficients are 0.58 and 0.57 for the a-helix and turn structures, respectively.
Ključne riječi
Hrčak ID:
137154
URI
Datum izdavanja:
29.1.1993.
Posjeta: 1.052 *