Medicinski vjesnik, Vol. 42 No. (3-4), 2010.
Review article
Application of surfactants in drug delivery systems
Darija Jurašin
Maja Dutour Sikirić
Abstract
Suifactants exhibit specific properties in water solutions — adsorption at interfaces and aggregation in different supramolecular structures (micelles, vesicles, liquid crystals). Such properties are consequence of the fact that surfactant molecule contains both hydrophilic and hydrophobic parts. Drug molecules themselves often behave as surfactants. Different surfactant phases are of interest in pharmacy, either for preparation of drug vehicles/carriers or targeting systems. Both of them protect body from unwanted side effects, while at the same time the optimal drug concentration is achieved at targeted site. Most of the work done in this field deals with surfactants as drug vehicles.
Keywords
Surface-active agents; Drug delivery systems; Pharmaceutical preparations
Hrčak ID:
191922
URI
Publication date:
1.12.2010.
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