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Contrast-induced nephropathy in patients with acute coronary syndrom after percutaneus coronary angiography and intervention

Tomislav Pavlović orcid.org/0000-0003-2841-6318 ; Sveučilište "Josipa Jurja Strossmayera" u Osijeku, Medicinski fakultet
Mia Dumančić ; Klinička bolnica "Sveti Duh", Zagreb, Zavod za radiologiju
Sanja Trtica orcid.org/0000-0002-9829-5606 ; Klinička bolnica "Sveti Duh", Zagreb, Zavod za radiologiju
Rosana Troskot Perić ; Klinička bolnica "Sveti Duh", Zagreb, Klinika za unutarnje bolesti
Ivica Brizić ; Sveučilišna klinička bolnica Mostar, Klinika za unutarnje bolesti

Sažetak

Some risk factors have a smaller or greater role in developing contrast-induced nephropathy (CIN). The purpose of this retrospective study is to contribute to the clarification of the risk factors and damage of contrast agents to the renal function after percutaneous coronary angiography and intervention. The research was conducted at the University Hospital Mostar, Department of Invasive Cardiology. The study included 235 patients with percutaneous coronary angiography and intervention procedure during 2013-2014 due to acute coronary syndrome. The data was collected from the database of the IT hospital system. We found the incidence of CIN in 14% of patients after percutaneous coronary angiography and intervention. In patients with CIN an average age was 69.3 ± 12.4 years as a statistically significant factor (p < 0.001). The mean amount of applied contrast agent during percutaneous coronary angiography and intervention in subjects with CIN was 331.8 ± 73.7 ml, which was statistically significant (p < 0.001). The number of diabetic patients within the CIN group was 60.6%, which was statistically significant (p < 0.001). Previously demonstrated renal insufficiency within the CIN group was 51.5%, statistically significant (p < 0.001). Comparison of intervention on coronary blood vessels with reference to the appearance of KIN did not show a statistically significant difference (p = 0.173). The emergence of CIN after percutaneous coronary angiography and intervention is more common in older patients, those with chronic kidney disease and diabetes mellitus. There is also a correlation between the amount of applied contrast agent and the CIN after percutaneous coronary angiography and intervention.

Ključne riječi

contrast media; coronary intervention; nephropathy

Hrčak ID:

208114

URI

https://hrcak.srce.hr/208114

Datum izdavanja:

6.11.2018.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.296 *