Kratko priopćenje
False-Positive Result of a Confirmatory Human Immunodeficiency Virus Line Immuno Assay in an Apparently Healthy Individual – A Case Report
Katja Seme
Božena Kotnik-Kevorkijan
Zvonko Baklan
Kristina Fujs
Dunja Z. Babič
Mario Poljak
Sažetak
A case of a false-positive result of human immunodeficiency virus (HIV) confirmatory immunoblot-based assay is described.
Repeatedly borderline reactive anti-HIV screening enzyme immunoassay result obtained in a local hospital resulted
in directing the sample to the Slovenian HIV/AIDS Reference Laboratory. In the Reference Laboratory, both anti-
HIV screening assays and confirmatory Western blot were negative, while a confirmatory test INNO-LIA HIV I/II Score
(Innogenetics, Ghent, Belgium) was anti-HIV-1 positive due to sgp120 and gp41 reactivity. The results of serological testing
of the second sample obtained three weeks later were completely identical, while in the third sample obtained 5
months later, seroreversion was observed. Due to a negative dynamics in anti-HIV serological profile and repeatedly negative
results of the molecular tests for HIV-1 and HIV-2, HIV infection was excluded and the results of test INNO-LIA
HIV I/II Score were finally interpreted as false positive.
Ključne riječi
HIV-1; diagnosis; false-positive result; confirmatory assays; line immuno assay
Hrčak ID:
27711
URI
Datum izdavanja:
25.4.2006.
Posjeta: 2.849 *