Sažetak sa skupa
Oral Pemphigus Vulgaris in a Young Adult - Case Report
Danica Juras
Ana Cekić-Arambašin
Sažetak
Pemphigus vulgaris is a rare, potentially lethal chronic autoimmune vesiculobullous disease of the skin and the mucous membrane. Most commonly it involves patients in their fifties and sixties and extremly rare in adolescence. Eighty to ninety percent of patient with pemphigus vulgaris develop oral lesions and 60% of cases oral lesions are the first sign. It is common for the oral lesions to be present up to 4 months before the skin lesions apper. The autors present a case of pemphigus vulgaris, which developed initially in an 18-year old girl and was confined to her mouth. Clinical and histopathological findings, also direct and indirect immunofluorescence studies of the oral mucosa confirmed the diagnosis of pemphigus vulgaris, with positive antibodies to desmoglein 3 and 1. The patient was successfully treated with systemic and topical corticosteroids in association with miconazole. The patient is treated with low-dose systemic corticosteroids, and during 11 years skin involvement has not been found. Recognition of oral lesions of adolescent pemphigus vulgaris by the clinician, its early diagnosis, and prompt therapy are important in order to eliminate or reduce the severity of further intraoral or extraoral involvement.
Ključne riječi
Hrčak ID:
3285
URI
Datum izdavanja:
15.9.2003.
Posjeta: 4.455 *