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Minimal Hepatic Encephalopathy in Patients with Decompensated Liver Cirrhosis

Daniela Marić
Biljana Klasnja
Danka Filipović
Snežana Brkić
Maja Ružić
Vojislava Bugarski

Puni tekst: engleski, pdf (217 KB) str. 375-380 preuzimanja: 776* citiraj
APA 6th Edition
Marić, D., Klasnja, B., Filipović, D., Brkić, S., Ružić, M. i Bugarski, V. (2011). Minimal Hepatic Encephalopathy in Patients with Decompensated Liver Cirrhosis. Acta clinica Croatica, 50 (3), 375-380. Preuzeto s https://hrcak.srce.hr/84110
MLA 8th Edition
Marić, Daniela, et al. "Minimal Hepatic Encephalopathy in Patients with Decompensated Liver Cirrhosis." Acta clinica Croatica, vol. 50, br. 3, 2011, str. 375-380. https://hrcak.srce.hr/84110. Citirano 20.11.2019.
Chicago 17th Edition
Marić, Daniela, Biljana Klasnja, Danka Filipović, Snežana Brkić, Maja Ružić i Vojislava Bugarski. "Minimal Hepatic Encephalopathy in Patients with Decompensated Liver Cirrhosis." Acta clinica Croatica 50, br. 3 (2011): 375-380. https://hrcak.srce.hr/84110
Harvard
Marić, D., et al. (2011). 'Minimal Hepatic Encephalopathy in Patients with Decompensated Liver Cirrhosis', Acta clinica Croatica, 50(3), str. 375-380. Preuzeto s: https://hrcak.srce.hr/84110 (Datum pristupa: 20.11.2019.)
Vancouver
Marić D, Klasnja B, Filipović D, Brkić S, Ružić M, Bugarski V. Minimal Hepatic Encephalopathy in Patients with Decompensated Liver Cirrhosis. Acta clinica Croatica [Internet]. 2011 [pristupljeno 20.11.2019.];50(3):375-380. Dostupno na: https://hrcak.srce.hr/84110
IEEE
D. Marić, B. Klasnja, D. Filipović, S. Brkić, M. Ružić i V. Bugarski, "Minimal Hepatic Encephalopathy in Patients with Decompensated Liver Cirrhosis", Acta clinica Croatica, vol.50, br. 3, str. 375-380, 2011. [Online]. Dostupno na: https://hrcak.srce.hr/84110. [Citirano: 20.11.2019.]

Sažetak
Minimal hepatic encephalopathy (mHE ) is characterized by some minimal unspecific alterations of cerebral functions that can only be detected by neuropsychological or neurophysiological diagnostic tests, which dysfunctions nevertheless interfere with the patient’s daily living. Early recognition of these impairments may prevent the progression or delay the development of the disease to overt hepatic encephalopathy. The aim of this study was to diagnose mHE in patients with decompensated liver cirrhosis. The study was conducted in 60 patients aged 40-65, divided into two groups: experimental group and control group. Patients in the experimental group were divided into Child-Pugh groups A, B or C: 53% were classified as Child-Pugh B and 47% as Child-Pugh C. Patients were tested using three neuropsychological tests: Mini Mental Score for quick assessment of cognitive status and two tests specific for mHE changes, Trail Making Test – Part A (TMT-A) and Symbol Digit Test (SDT ). Electroencephalography (EEG) was performed in all patients. Limits for completing the test were set by using the formula Xcontrol group + 2 SD for TMT-A and Xcontrol group - 2 SD for SDT . All the three tests disclosed statistically significantly different results between the two groups. All patients with cirrhosis had some changes in EEG. Study results showed 80% of cirrhosis patients to have signs of mHE . The Child-Pugh score influenced performance on the neuropsychological tests. SDT more readily identified patients with mHE . Our findings pointed to the frequency of mHE and the importance of early diagnosis in the prevention of mHE progression to overt hepatic encephalopathy.

Ključne riječi
Hepatic encephalopathy; Psychomotor disorders; Neuropsychological tests; Electroencephalography

Hrčak ID: 84110

URI
https://hrcak.srce.hr/84110

[hrvatski]

Posjeta: 1.124 *