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Review article


SANJA POPOVIĆ-GRLE ; Zagreb University Hospital Center, Jordanovac Department for Lung Diseases, Zagreb, Croatia

Fulltext: croatian, pdf (171 KB) pages 141-146 downloads: 2.232* cite
APA 6th Edition
POPOVIĆ-GRLE, S. (2011). ALERGIJSKE BOLESTI I PUŠENJE. Acta medica Croatica, 65 (2), 141-146. Retrieved from
MLA 8th Edition
POPOVIĆ-GRLE, SANJA. "ALERGIJSKE BOLESTI I PUŠENJE." Acta medica Croatica, vol. 65, no. 2, 2011, pp. 141-146. Accessed 21 Apr. 2021.
Chicago 17th Edition
POPOVIĆ-GRLE, SANJA. "ALERGIJSKE BOLESTI I PUŠENJE." Acta medica Croatica 65, no. 2 (2011): 141-146.
POPOVIĆ-GRLE, S. (2011). 'ALERGIJSKE BOLESTI I PUŠENJE', Acta medica Croatica, 65(2), pp. 141-146. Available at: (Accessed 21 April 2021)
POPOVIĆ-GRLE S. ALERGIJSKE BOLESTI I PUŠENJE. Acta medica Croatica [Internet]. 2011 [cited 2021 April 21];65(2):141-146. Available from:
S. POPOVIĆ-GRLE, "ALERGIJSKE BOLESTI I PUŠENJE", Acta medica Croatica, vol.65, no. 2, pp. 141-146, 2011. [Online]. Available: [Accessed: 21 April 2021]

Cigarette smoking is a major risk to the overall burden of disease in developed countries. Smoking influences disease development, disease outcome and therapeutic success. Cigarettes with low tar, which do less harm, do not exist, nor there is a safe level of smoking. Passive smoking is involuntary inhalation of tobacco smoke. Environmental tobacco smoke is the second most common cause of carcinogen exposure. Passive smoking, whether prenatal or postnatal in children, increases the likelihood of asthma, similar as in adults. Active smoking increases total immunoglobulin E (IgE) level and inflammatory cell infiltration, especially eosinophils. Tobacco smoking increases bronchial hyperreactivity. Clinical picture of asthma in smokers is more severe in terms of symptoms, with more frequent exacerbations and invasive intubation with increased mortality rate than in asthmatics nonsmokers. Smokers have a higher prevalence of allergic rhinitis and atopic dermatitis.

smoking; passive smoking; immunoglobulin E; bronchial hyperreactivity; asthma, allergic rhinitis; atopic dermatitis

Hrčak ID: 87892



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